Braxford Journal

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Plant sterols and stanols

Plant sterols and stanols are natural compounds found in various plant-based foods that resemble cholesterol in structure. They are primarily derived from vegetable oils, nuts, seeds, and whole grains. These compounds are known for their cholesterol-lowering properties, as they can inhibit the absorption of dietary cholesterol in the intestines.

    • Can improve:
    • Can prevent:
      • coronary heart disease | cardiovascular disease ? [ h | i ]
    • Reduces:
      • low-density lipoprotein (LDL) [ a | b | c | d | e | g ]
      • fasting plasma glucose levels [ a ]
      • total cholesterol (TC) [ a | e | g ]
      • atherosclerotic lesion development | atherosclerotic risk [ c ]
    • Increases:
    • Side-effects:
    • Safety profile (C):
      • Safe [ f ]
      • Negative
        • a link between elevated plasma concentrations of circulating plant sterols with CVD presence [ a ]
        • a potential role in the development of non-alcoholic steatohepatitis (NASH), cardiovascular disease (CVD), inflammatory bowel diseases (IBD) and allergic asthma [ c ]

    Dosage

      Moderate/Beneficial2 g/day [ a | h ]
      2.5 g/day [ g ]

      Notes

      ? – Contradictory studies.

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